Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML
Faisal Basheer, George Giotopoulos, Eshwar Meduri, Haiyang Yun, Milena Mazan, Daniel Sasca, Paolo Gallipoli, Ludovica Marando, Malgorzata Gozdecka, Ryan Asby, Olivia Sheppard, Monika Dudek, Lars Bullinger, Hartmut Döhner, Richard Dillon, Sylvie Freeman, Oliver Ottmann, Alan Burnett, Nigel Russell, Elli Papaemmanuil, Robert Hills, Peter Campbell, George S Vassiliou, Brian J P Huntly
Correction: Corrigendum: Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
Marco Sciacovelli, Emanuel Gonçalves, Timothy Isaac Johnson, Vincent Roberto Zecchini, Ana Sofia Henriques da Costa, Edoardo Gaude, Alizee Vercauteren Drubbel, Sebastian Julian Theobald, Sandra Riekje Abbo, Maxine Gia Binh Tran, Vinothini Rajeeve, Simone Cardaci, Sarah Foster, Haiyang Yun, Pedro Cutillas, Anne Warren, Vincent Gnanapragasam, Eyal Gottlieb, Kristian Franze, Brian Huntly, Eamonn Richard Maher, Patrick Henry Maxwell, Julio Saez-Rodriguez, Christian Frezza
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
Marco Sciacovelli, Emanuel Gonçalves, Timothy Isaac Johnson, Vincent Roberto Zecchini, Ana Sofia Henriques da Costa, Edoardo Gaude, Alizee Vercauteren Drubbel, Sebastian Julian Theobald, Sandra Riekje Abbo, Maxine Gia Binh Tran, Vinothini Rajeeve, Simone Cardaci, Sarah Foster, Haiyang Yun, Pedro Cutillas, Anne Warren, Vincent Gnanapragasam, Eyal Gottlieb, Kristian Franze, Brian Huntly, Eamonn Richard Maher, Patrick Henry Maxwell, Julio Saez-Rodriguez, Christian Frezza
Genetic characterization of acquired aplastic anemia by targeted sequencing
Michael Heuser, Carola Schlarmann, Vera Dobbernack, Victoria Panagiota, Lutz Wiehlmann, Carolin Walter, Fabian Beier, Patrick Ziegler, Haiyang Yun, Sofia Kade, Aylin Kirchner, Liu Huang, Christian Koenecke, Matthias Eder, Tim H. Brümmendorf, Martin Dugas, Arnold Ganser, Felicitas Thol
Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML
Anuhar Chaturvedi, Michelle Maria Araujo Cruz, Nidhi Jyotsana, Amit Sharma, Haiyang Yun, Kerstin Görlich, Martin Wichmann, Adrian Schwarzer, Matthias Preller, Felicitas Thol, Johann Meyer, Reinhard Haemmerle, Eduard A. Struys, Erwin E. Jansen, Ute Modlich, Zhixiong Li, Laura M. Sly, Robert Geffers, Robert Lindner, Dietmar J. Manstein, Ulrich Lehmann, Jürgen Krauter, Arnold Ganser, Michael Heuser
Incidence and Prognostic Influence of DNMT3A Mutations in Acute Myeloid Leukemia
Felicitas Thol, Frederik Damm, Andrea Lüdeking, Claudia Winschel, Katharina Wagner, Michael Morgan, Haiyang Yun, Gudrun Göhring, Brigitte Schlegelberger, Dieter Hoelzer, Michael Lübbert, Lothar Kanz, Walter Fiedler, Hartmut Kirchner, Gerhard Heil, Jürgen Krauter, Arnold Ganser, Michael Heuser
Cell of Origin in AML: Susceptibility to MN1-Induced Transformation Is Regulated by the MEIS1/AbdB-like HOX Protein Complex
Michael Heuser, Haiyang Yun, Tobias Berg, Eric Yung, Bob Argiropoulos, Florian Kuchenbauer, Gyeongsin Park, Iyas Hamwi, Lars Palmqvist, Courteney K. Lai, Malina Leung, Grace Lin, Anuhar Chaturvedi, Basant Kumar Thakur, Masayuki Iwasaki, Mikhail Bilenky, Nina Thiessen, Gordon Robertson, Martin Hirst, David Kent, Nicola K. Wilson, Bertie Göttgens, Connie Eaves, Michael L. Cleary, Marco Marra, Arnold Ganser, R. Keith Humphries
Prognostic Significance of ASXL1 Mutations in Patients With Myelodysplastic Syndromes
Felicitas Thol, Inna Friesen, Frederik Damm, Haiyang Yun, Eva M. Weissinger, Jürgen Krauter, Katharina Wagner, Anuhar Chaturvedi, Amit Sharma, Martin Wichmann, Gudrun Göhring, Christiane Schumann, Gesine Bug, Oliver Ottmann, Wolf-Karsten Hofmann, Brigitte Schlegelberger, Michael Heuser, Arnold Ganser
Single Nucleotide Polymorphism in the Mutational Hotspot of WT1 Predicts a Favorable Outcome in Patients With Cytogenetically Normal Acute Myeloid Leukemia
Frederik Damm, Michael Heuser, Michael Morgan, Haiyang Yun, Anika Großhennig, Gudrun Göhring, Brigitte Schlegelberger, Konstanze Döhner, Oliver Ottmann, Michael Lübbert, Wolfgang Heit, Lothar Kanz, Günter Schlimok, Aruna Raghavachar, Walter Fiedler, Hartmut Kirchner, Hartmut Döhner, Gerhard Heil, Arnold Ganser, Jürgen Krauter